Amikacin

Please note: This is for information only.

Refer to local guidelines for treatment recommendations 


 

  • An aminoglycoside antibiotic
  • Bactericidal
  • Can be given IV or IM. No oral preparation available.
  • Once daily dosing recommended (see local policy)
  • Divided dose regimen (adult) usually 15mg/kg in two divided doses (max. 750mg bd)
  • Renally excreted therefore adjust dose in renal impairment
  • Adjust dose in obese patients.
  • Monitor blood levels closely and adjust dose accordingly.
  • Patient needs to be hydrated well during therapy.

Main indications:

  • Microbiology advice
  • Resistant pseudomonas infections

Active against most strains of:

  • Staphylococcus aureus (including MRSA)
  • Escherichia coli
  • Pseudomonas
  • Klebsiella
  • Salmonella
  • Acinetobacter

Not active against most strains of:

  • Streptococci
  • Anaerobes