Please note: This is for information only.
Refer to local guidelines for treatment recommendations
- A lincosamide antibiotic.
- No dosage adjustment necessary in renal impairment
- Adjust dose in hepatic impairment
- Avoid co-administration with erythromycin or neuromuscular blocking agents.
- Very good bioavailability when given orally
- Good penetration into tissue and bone.
- High risk of Clostridium difficile antibiotic-associated diarrhoea if prescribed for elderly inpatients.
- Serious streptococcal infections (eg: cellulitis), in combination with or as an alternative to benzylpenicillin.
- Second line agent for serious soft tissue infections due to S aureus
- Alternative to metronidazole for anaerobic infections.
Active against most strains of:
- Haemolytic streptococci
- Staphylococcus aureus – including some MRSA
Not active against most strains of:
- Eschericia coli
- Pseudomonas aeruginosa