Please note: This is for information only.
Refer to local guidelines for treatment recommendations
- A Gram-negative bacillus - the principal member of the enterobacteria family (Coliforms).
- A common commensal in the gastro-intestinal tract.
- The most common organism encountered in urinary tract infections.
- Some biotypes of E coli are also enteric pathogens, causing diarrhoea. In particular, E coli O157 which causes haemorrhagic colitis and haemolytic uraemic syndrome. Infection control precautions are required for these strains.
Main clinical infections:
- Urinary tract infections (principal cause).
- Intra-abdominal infections e.g. appendicitis, perforations, peritonitis.
- Ventilator-associated pneumonia. (Other chest infections are very rare.)
Usually sensitive to:
- Quinolones (Ciprofloxacin, Levofloxacin)
- Aminoglycosides (Amikacin, Gentamicin, Tobramycin)
Usually resistant to:
- Amoxicillin : resistance is common (50-60%).
- Resistance against trimethoprim and quinolones is also on the increase.