Helicobacter

Please note: This is for information only.

Refer to local guidelines for treatment recommendations.


  • Gram-negative spiral rods, difficult to isolate from clinical samples as slow growing.
  • Breaks down urea using the enzyme urease.
  • Culture is now rarely required, mainly done on biopsies to test for antibiotic sensitivity and follow up as diagnosis is usually confirmed by the urea breath test or serological evidence of infection.

Main clinical infections:

  • Chronic peptic ulcer, dyspepsia (refractory to conventional treatment), gastric MALT.

Usually sensitive to:

Click here for H. pylori eradication guideline

Usually resistant to:

  • Trimethoprim