Neisseria: N. gonorrhoea (gonococci) and N. meningitidis (meningococci)
Please note: This is for information only.
Refer to local guidelines for treatment recommendations
- Gram-negative intracellular diplococci
- Meningococci can be present in patients saliva during the first 48 hours of admission. Masks should therefore be worn for endotracheal intubation or suctioning and patients nursed in a side room for the first 48 hours if possible.
- Diagnosis can be made by looking for meningococcal DNA by PCR on EDTA samples, as well as blood cultures and CSF cultures.
Main clinical infections:
- Meningitis and / or septicaemia
- Pneumonia in the elderly
- Occasionally septic arthritis.
- Vaginal / penile discharge
- Pelvic inflammatory diseases.
- Occasionally disseminated infection with septic arthritis.
Usually sensitive to:
- For treatment: Penicillin, 3rd generation cephalosporins (ceftriaxone, cefotaxime)
- For eradication of carriage: rifampicin, ciprofloxacin, ceftriaxone
- Third generation cephalosporins eg ceftriaxone.
Usually resistant to:
- Increasing problem of resistance to penicillin so only used for treatment if known sensitive strain.
- Resistance to the quinolone antibiotics (ciprofloxacin, levofloxacin) is rising