Helicobacter pylori eradication

Recommended: as per NICE guidelines:

Omeprazole 20mg po bd
Plus
CLARITHROMYCIN 250mg po bd
Plus 
METRONIDAZOLE 400mg po bd

  } For 1 week

  

Alternative:

Omeprazole 20mg po bd
Plus
CLARITHROMYCIN 500mg po bd
Plus
AMOXICILLIN 1g po bd

  } For 1 week

 

  • Following eradication of H. pylori associated with duodenal ulcers uncomplicated by haemorrhage or perforation, the British Society of Gastroenterology (BSG) recommends that continued proton pump inhibitor (PPI) is not required.
  • For H. pylori associated with gastric ulcers, the BSG recommend continuing with 2 months of PPI following eradication, or until healing is confirmed at endoscopy.

 

Specific indication: (for patients who have failed on the recommended regimen): 

Omeprazole 20mg po twice daily
Plus
METRONIDAZOLE 400mg po tds
Plus
TETRACYCLINE 500mg po qds

  } For 2 weeks

 

Last updated 29/04/2014