Spontaneous Bacterial Peritonitis

 

For Peritoneal Dialysis Related Peritonitis (click here). Please contact Specialist Nurse on Ward 7b GRH or the duty Nephrologist.

Severity
(classification)

1st line oral/iv antibiotics

Penicillin allergy
(see explanatory notes)

A/B/C

Minor to severe life threatening infection

Review doses in renal impairment

TAZOCIN 4.5g iv tds (monotherapy)

If definite history of rash allergy but no anaphylactic penicillin allergy (see explanatory notes), use:
 

Treatment duration: 5 - 7 days according to clinical response. Then see IV to Oral Switch below (unless lab results indicate otherwise)

Non-Severe Penicillin Allergy:

MEROPENEM 1g iv tds

 

Severe Penicillin Allergy:

TIGECYCLINE 100mg iv stat as loading. Then 50mg iv bd (25mg bd in severe hepatic disease)
plus
GENTAMICIN iv (as per local protocol)

 

Treatment duration: 5 - 7 days according to clinical response. Then see IV to Oral Switch below (unless lab results indicate otherwise)

IV to Oral Switch
(explanatory notes)

CO-AMOXICLAV 625mg po tds

Treatment duration: 5 - 7 days according to clinical response.

Note: Discuss need for ongoing antibiotic prophylaxis with Gastroenterologist

 

CIPROFLOXACIN 500mg po bd
plus
METRONIDAZOLE 400mg po tds

Treatment duration: 5 - 7 days according to clinical response.

Note: Discuss need for ongoing antibiotic prophylaxis with Gastroenterologist

Last reviewed: 14/8/13 

For guidance on the administration of intravenous antibiotics click here
(GHNHSFT intranet)