Periorbital cellulitis

If necrotising fasciitis suspected consult microbiology urgently

Severity
(classification)

1st line oral/iv antibiotics

Penicillin allergy
(see explanatory notes)

A/B/C

Minor to severe life threatening infection

 

Review doses in renal impairment

CEFTRIAXONE 2g iv bd
plus
CLINDAMYCIN 1.2g iv qds
STOP and review if patient develops diarrhoea

 

  • If suspected/confirmed MRSA, initially ADD:

TEICOPLANIN iv every 12 hours for 4 doses then once daily.

Dose

<50kg: 400mg

50-74kg: 600mg

75-100kg: 800mg

>100kg: 1000mg 

Maintain treatment pending pre-dose (trough) level on Day 5. Target level 15-60mg/L. (Click for dosing table)

LINEZOLID 600mg po/iv bd
plus
CIPROFLOXACIN 750mg po bd
plus
METRONIDAZOLE 400mg po tds or 500mg iv tds.

 

  • If suspected/confirmed MRSA, note LINEZOLID has activity against MRSA

 

 

Last Reviewed: 12/02/14 

For guidance on the administration of intravenous antibiotics
click here (GHNHSFT intranet only)