EBV (glandular fever) antibodies




  • This investigation is used to diagnose Epstein Barr Virus infection
  • The investigation comprises three tests:
    • EBVNA IgG
    • EBV VCA IgG
    • EBV IgM
  • A positive EBVNA IgG result indicates infection more than six weeks previously
  • A positive EBV VCA IgG result indicates infection at some time
  • An EBV IgM is performed on all children under 16 years
  • EBV viral loads are useful for the diagnosis of active EBV infection in immuno-compromised patients, including PTLD (see EBV viral load)
  • This test is part of the following viral screen sets:
  • See also Throat swab

Sample requirements

Serum - paired samples not required

8.5ml of blood taken into a plain gel tube 

8.5mL BD Vacutainer tube

Required information

  • Relevant clinical details
  • Date of onset
  • Jaundice, abnormal LFTs
  • Lymphadenopathy, malaise, myalgia, flu-like illness
  • Glandular Fever


Store at fridge temperature

Transport as soon as possible at ambient temperature

Turnaround time

7 - 10 days

Page last reviewed: 27/11/2013