Carbapenamase-Producing Enterobacteriaceae (CPE) screen
- Carbapenamase-producing Enterobacteriaceae (CPE) are resistant not only to carbapenems (considered “last resort” antibiotics) but also all penicillin-type antibiotics and cephalosporins. CPE also commonly carry resistance genes to other groups of non-beta-lactam antibiotics, making them highly multiply resistant and extremely difficult to treat with antibiotics when patients have clinical infections caused by these bacteria.
- Screening is undertaken according to risk assessment on admission - see CPE: Prevent. Detect. Control (Trust users only)
- See Infection Control policy "Multi-drug resistant bacteria (excluding MRSA): management of infected or colonised patients"
- All potential CPE isolates are referred to the National Reference Laboratory for confirmation.
- The following samples are required:
- Rectal swab (or stool sample if a rectal swab is not possible)
- Wounds and entry sites
- Urine if catheterised
- Risk factors
- Recent relevant hospital admissions
- Relevant overseas health care
- Known previous colonisation/infection with CPE
- Contact with colonised patients
Store and transport at room temperature
Negative: 2-3 days
Positive: 2-4 days for provisional result, Reference laboratory confirmation will take longer.
Page last reviewed: 23/08/2014