- Toxoplasma is a parasite that can cause a glandular fever like illness and may affect a foetus during pregnancy. It can reactivate in immunocompromised patients, for example causing cerebral toxoplasmosis in AIDS
The laboratory performs a serological Toxoplasma screening test that will be referred to the reference lab if positive.
- Normally a level of <10iu/ml indicates no previous Toxoplasma infection. However in the setting of HIV infection, severe immunocompromise and ocular Toxoplasma infection a lower threshold of <4 iu/ml is taken as negative and any sample with levels above threshold is referred to the National Reference Lab, Swansea for further investigation including IgM tests.
Toxoplasma antibody avidity testing is also available on discussion with a Microbiologist (this may be useful for possible pregnancy associated infection).
Toxoplasma nucleic acid detection assays (e.g. PCR) can be performed on vitreous and aqueous fluid samples or an EDTA blood sample. Please discuss with the laboratory.
This test is part of the following viral screen sets:
Serum - paired samples normally required
8.5ml of blood taken into a plain gel tube
- Relevant clinical details
- Date of onset
- Pregnancy including gestational age
Store at fridge temperature
Transport as soon as possible at ambient temperature
Positives referred to a National Reference Centre
Negatives: 3 - 5 days
Positives: 10 - 14 days
Page last reviewed: 25/11/2013