Cryoglobulins
Department of Immunology
Notes
- Sample must be taken and maintained at 37°C
- Please ensure all equipment is warmed to 37°C prior to taking the sample.
- If unsure about sample requirements, or if a hot box is required for sample transport, please contact the Immunology laboratory
- This test is useful in some cases of vasculitis
- Positive cryoglobulin samples are referred to the Immunology laboratory at Northern General Hospital, Sheffield for cryoglobulin phenotyping.
- Please note: this test does not conform to CPA standard H5.4 as no external quality assurance scheme is available. Therefore, this test is not accredited by CPA.
Sample Requirements
Adult
![9ml serum clot activator](https://www.gloshospitals.nhs.uk/media/images/9_mL_serum_clot_activator.width-800.jpg)
Paediatric
![1ml serum tube](https://www.gloshospitals.nhs.uk/media/images/1_mL_serum.width-800.jpg)
Turnaround Times
- 7–10 days (positive / negative screen)
- 3–4 weeks (fully phenotyped cryoglobulin; if positive)