Cytomegalovirus (CMV) antibodies

Microbiology

Notes

The information given here is intended for use by healthcare professionals. Please see Lab Tests Online-UK for more general advice, links and background.

Tests available include:

• CMV IgM
  
• CMV IgG
  
• CMV avidity
  
• In the case of a raised CMV IgG result a CMV IgM test is performed
  
• A positive CMV IgM result indicates recent infection
  
• If CMV IgM positive, direct detection of virus by PCR viral load is indicated (see CMV viral load)
  
• CMV IgG is used to diagnose previous CMV infection
  
• CMV avidity can be used to indicate how recently infection has occurred. This is usually of use in pregnancy and should only be requested after discussion with a Consultant Microbiologist
  

Sample requirements

Serum - paired samples not required

8.5ml of blood taken into a plain gel tube

Required information

• Relevant clinical details
  
• Date of onset
  
• For acute CMV - jaundice, abnormal LFTs, lymphadenopathy
  

Storage/transport

Store at fridge temperature

Transport as soon as possible at ambient temperature

Turnaround time

7–10 days