Leptospira antibodies (weils)

Microbiology

Notes

• The test detects Leptospiral IgM antibodies
• A rise in antibody titres may take up to 2 weeks following acute infection
• Urine testing for Leptospirosis is no longer available
• Acute Leptospirosis (within the first three days) can be diagnosed by nucleic acid detection assays (e.g. PCR) on an EDTA blood sample. Please discuss with the laboratory.

Sample requirements

Serum - paired samples normally required

8.5ml of blood taken into a plain gel tube

Required information

• Relevant clinical details
• Date of onset
• Date of possible exposure
• Exposure history - occupation, leisure activities

Storage/transport

Store at fridge temperature

Transport as soon as possible at ambient temperature

Turnaround time

Sent to a National Reference Centre

10 - 14 days